Genetic Condition Information & Testing

 

Parental Testing Form

Genetic Testing Form

DNA Testing Options

Important Information – The DNA Testing Submission Form must be completely filled out when it is sent to the ASA office. Be sure to include tattoo, Reg #, sex, DOB, Sire Reg #, and Dam Reg # on each animal you are submitting for testing. Forms that are incomplete are subject to a processing fee. – A $2/sample fee will be charged to all hair samples. GeneSeek has implemented this fee due to increased processing and a higher percentage of retesting with hair samples. – GeneSeek recommends using tissue samples as their preferred method of genetic testing. Tissue samples are preferred due to their ease of sampling, longer storage life, and quicker turnaround time. Tissue samples are taken using an Allflex applicator tool to remove a sample from the animal’s ear into a small tube for storing the sample. If you are interested in using tissue sampling, contact GeneSeek to order your applicator tool and sample collection units. – If you have any questions regarding DNA testing, please contact the ASA office.

Available Tests
Test That Satisfy AI Sire/Donor Dam Requirements

GGP-LD 50K with TH, PHA, DS: $80 This testing for AI Sire/Donor Dam requirements includes parent verification, a GGP-LD 50K DNA profile, and testing for known genetic conditions (TH, PHA, DS). Selecting animals for this test will allow them to have genomically-enhanced EPDs (GE-EPDs).

GGP-150K with TH, PHA, DS: $125 This testing for AI Sire/Donor Dam requirements includes parent verification, a GGP-F250 (250K) DNA profile, and testing for known genetic conditions (TH, PHA, DS). Selecting animals for this test will allow them to have genomically-enhanced EPDs (GE-EPDs). Genomic Profiles (GGP Products)

GGP– HD 150K: $90 This is a high density (150K) testing panel that includes parentage markers. This test is recommended for elite sires and donor dams with large numbers of progeny. Selecting this profile will allow the animal to receive GE-EPDs.

GGP-LD 50K: $55 This is a low density (50K) testing panel that includes parentage markers. Animals with the LD-50K profile will receive GE-EPDs.

GGP-uLD 25K: $40 The markers on the GGP-uLD profile are used to calculate GE-EPDs. The available markers on the GGP-uLD can be imputed to the equivalence of the GGP-LD 50K. The GGP-uLD is recommended for young bulls, replacement heifers, or testing the entire cow herd. Genetic Conditions and Stand Alone Tests

Testing for genetic conditions and stand-alone products can be ordered independently of GGP products. However, animals tested for genetic conditions without a genomic profile will NOT have GE-EPDs available. All genetic condition and parentage tests (both bundle and stand-alone) are automatically loaded into the Digital Beef registry if the test is run through GeneSeek

TH, PHA, DS Bundle: $48
Parentage Markers: $35
Tibial Hemimelia (TH): $27
Pulmonary Hypoplasia with Anasarca (PHA): $27
Digital Subluxation (DS): $27
Fescue Toleranc

Fesuce Tolerance DNA Test: $27 The test for fescue tolerance developed by AgBotanica identifies genetic markers that indicate an animal’s ability to tolerate toxic fescue. Outputs from the test will give you a numeric score (0 to 50, with 50 being the highest) on the online registry, as well as the $Fescue in

dex. Cattle that have not been tested for fescue tolerance will not have $Fescue available.

Genetic Testing Policy

Below are the current rules and regulations from the ASA in regards to Genetic Condition and DNA genotyping.

Section 8. DNA GENOTYPING/GENETIC CONDITION TESTINGS

  1. DNA GENOTYPING: DNA genotyping is utilized in establishing parentage and may also be used in determining the presence a genetic
    1. General: Animals do not have to be DNA genotyped to be registered. However, if an animal becomes an A.I. sire or a donor dam, all required genetic testing must be completed and a DNA genotype will be parent verified, whenever possible, on file with the ASA prior to registering any progeny. If an A.I. sire or donor dam has died or the resulting progeny do not have the appropriate DNA for all known genetic conditions on file with the ASA, then the resulting calves can only be registered after the same tests for A.I. Sire or Donor Dam qualifications are met for each AI and/or embryo calf.
    2. Random DNA Genotyping: At the discretion of the ASA Board of Directors, random DNA genotyping may be performed. Failure to cooperate with an ASA request within (30) days of notification, will result in sanctions as deemed appropriate as provided in Article II, Section 7 & Section 8 of the ASA Bylaws, including without limitation the suspension of the owner’s membership and suspension of the animal’s registration
    3. Analysis: All DNA samples shall be analyzed by the ASA’s designated laboratory and an interpretation shall be rendered by the laboratory’s director.
    4. Satellite (STR) Markers Previous to May 1, 2014: All animals in the registry with STR DNA (Satellite) markers which identify them as having the proper verified parentage previous to May 1, 2014 have their parentage verification grandfathered into the registry. These resulting animals will be accepted in the registry as is and grandfathered in – with the technology used at the time they were tested to determine parentage – confirming they were parent verified. Animals that fall in this category will continue to maintain their Donor Dam and AI Sire Qualified status in relation to their DNA parentage verification requirements. However, any future progeny or animals resulting from STR DNA tested parents after May 1, 2014 will only be accepted for parentage verification by being tested with SNP (snip) Markers.
  1. GENETIC CONDITION TESTING: The following points represent the ASA policy on Genetic Condition
    1. As of July 1, 2016, all AI sires, donor dams and cloned animals must be DNA genotyped and genetic condition tested at an approved ASA DNA lab with results reported to the ASA. If an A.I. sire or donor dam has died or the resulting progeny do not have the appropriate DNA for all known genetic conditions on file with the ASA, then the resulting calves can only be registered after the required tests for A.I. Sire or Donor Dam qualifications are met for each embryo calf.
    2. A.I. certificates will be issued regardless of genetic condition status, and ET calves will be eligible for registration as long as results are in compliance with Rule III Section 8.C
    3. A listing of genetic condition status for bulls and cows shall be available at the ASA if the results have been released to ASA. This listing will be made available upon request.
    4. Registration certificates will be issued regardless of genetic condition status as long as results are in compliance with Rule III Section 8C.
    5. ASA reserves the right to conduct random genetic condition testing.
    6. All cattle consigned to ASA sanctioned sales must be phenotype/genetically tested, per ruling by the ASA board for ASA sponsored sale. Testing must be completed prior to cataloging and/or sale as established by ASA board.
    7. The owner of any animal suspected of death as the result of a genetic condition shall contact the ASA office immediately and follow the appropriate protocol.
    8. Breeders who misrepresent the genetic condition status of any animal are subject to fraud as defined in Rule II, Section 2, A.

C.  Homozygous Genetic Condition Explanation: The DSH individual has two copies of the genetic condition and will pass an unfavorable copy of the condition on to 100% of its progeny. The progeny will only receive one copy of the genetic condition from the DSH parent. However, the progeny could receive another copy from the other parent if said sire or dam is DSC or DSH. Calves from a sire and dam that is a carrier (DSC), have the possibility (25%) of getting two copies and could be homozygous for the conditions (DSH).

  1. As of 1/1/2016, any animal in the breeding population that is suspect or listed as probable in the registry to be homozygous for a non-lethal genetic condition must be tested for that genetic condition to be eligible for registration into the ASA herd book. The result of the test will have no effect on the eligibility for registration. The listing below is an example of when testing is required:
    • DSC x DSC = Testing Required
    • DSC x DSH= Testing Required

Progeny from the DS mating combinations below will be allowed to register without testing:

  • DSC x DSF= No testing required
  • DSF x DSF= No testing required
  1. Definition of non-lethal (Homozygous) Homozygote: (DSH) Any animal, regardless of breed background, pedigree, sex, or age that possesses two copies of a known Genetic Condition not causing death or normal biologic Homozygous status will be determined via DNA testing through approved laboratories.
  • The genetic conditions will be reflected on the pedigree for three It is recommended that the potential carriers be tested. If the trace on the pedigree leads to a homozygote, then the resulting progeny must be tested until the status of the known Genetic Condition is verified.
  1. The testing must be from an ASA approved
  2. This rule applies to any and all known non-lethal genetic conditions as they become identified in the future via DNA
  3. The ASA relies on testing results from outside labs and is therefore in no way liable for inaccurate data reported to

A.    Color Coding on Pedigree to Identify Genetic Conditions

  1. The ASA board approved a search on the new pedigrees when issued for three generations back from the individual animal (generations seen on the normal three generation pedigree) for Genetic Conditions that may have potential carriers that have not been tested from known carriers. In order to find animals that may be at risk of being carriers of Genetic Conditions, it was approved to color code individual genetic conditions codes on pedigrees and online searches to show an animal’s status of genetic conditions. Animals that have tested free of genetic conditions will have their Genetic Condition code shown in Green font. Animals that have been tested and are known carriers of Genetic Conditions will have their Genetic Condition code shown in Red font. Animals that are progeny of a descendant from known carriers (Red) and not tested will have their Genetic Condition code shown in Yellow/Orange font to indicate a potential carrier or animal at risk of being a carrier. The owners of animals which have a possibility of being potential carriers, due to being a descendant of a known carrier, shall be asked to have the animals in question tested. If the known carrier is a homozygote carrier of a non-lethal genetic condition the resulting animals would need to be tested according to rules, (Section Rule III, 8, C) for Homozygous Genetic Conditions. The ASA relies on data provided by outside sources and as such makes no representation as to the accuracy of the data provided to the ASA. In consideration for the privilege to register an animal, all members waive all claims against the ASA, its board of directors, employees or agents for inaccurate data and agree that claims may be brought only against the testing entities and/or the registry software.

Please note testing may take up to 30 days.  Please plan accordingly when testing your animals if you have a deadline!

Genetic Testing Status Tool

To obtain any Shorthorn animal’s genetic defect status, use the “Search the Breed” link below. Type the animal’s registered name or registration number in the spaces provided and then click “Search.” If the animal has been tested and reported to the ASA, the genetic defect status will appear right after the animal’s registration number at the top of the “Animal Information” page. If nothing is listed, then the animal’s genetic condition status has not been reported to the ASA.

SEARCH THE BREED